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Student Well-Being What the Research Says

Teen Brains Aged Prematurely During the Pandemic. 69传媒 Should Take Note

By Sarah D. Sparks 鈥 December 02, 2022 3 min read
Cracked silhouette of a person holding their head with illuminated gears in place of the brain.
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Teenagers鈥 brains aged years in a matter of months during the stress and isolation of the pandemic lockdowns.

A new study published in the journal suggests that the pandemic caused similar effects to emotion and decisionmaking centers in the brain as chronic, toxic stress.

Researchers began tracking the development of more than 200 9- to 13-year-olds in Santa Clara County, Calif., in 2016. A ten-months-long lockdown in 2020 put that work on hiatus, but also created a natural experiment to test how the students were affected by the widespread social isolation, school disruption, financial instability, and health stresses.

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鈥淓very adolescent in the country went through the pandemic. ... and this is what we鈥檙e seeing as a consequence of having experienced yearlong lockdown,鈥 said Ian Gotlib, professor and director of the at Stanford University and lead author of the study. 鈥淲e know that early adversity and stress can accelerate biological aging and brain maturation. It wasn鈥檛 so much the direction of the brain aging that surprised us; it was how pronounced it was for such a relatively short period of time.鈥

Compared to teenagers coming of age before the pandemic, those who experienced 10 months of lockdowns in 2020 showed three to four years of premature aging in the brain鈥檚 amygdala, hippocampus, and cerebral cortex.

Stress 鈥榓ging鈥 in the brain

The cerebral cortex鈥攖he tightly folded bundle of neurons that makes up the outer layer of the brain鈥攊s associated with higher reasoning, language, and memory. It naturally thins as people age. Similarly, the hippocampus, also associated with concentration, learning, and memory, and the amygdala, associated with emotional regulation and impulse control, grow as children mature.

However, prior studies have shown that children who experience severe adversity, such as abuse or neglect, show , seen in thinned cortices and swelled amygdala and hippocampic regions of the brain. When related to toxic stress, these changes are in turn associated with higher risk of memory and learning problems and mental illnesses such as anxiety and depression鈥攚hich may help to explain the sharp rise in mental health disorders among teenagers since the pandemic.

鈥淚t may not mean all that much that a 15-year-old鈥檚 brain looks like the brain of an 18- or 19-year-old,鈥 Gotlib said. 鈥淏ut it鈥檚 the anxiety and depression and suicidal ideation and sadness and fearfulness鈥攖hat spike that we鈥檙e seeing in the deterioration of mental health that I think is so important. And we鈥檝e shown that it鈥檚 accompanied by alterations in the brain.鈥

But Gotlib鈥檚 findings don鈥檛 mean that teenagers won鈥檛 be able to recover academically or emotionally post-pandemic. Brain plasticity鈥攖he ability to adapt to new information and environments鈥攊sn鈥檛 really that different among adolescents of different ages.

Rather, he said, 鈥淚 would want [school staff] to pay attention to the mental health data and be sure that they鈥檙e trying to support teens who are showing signs of emotional distress in any way that they can.鈥

In one recent survey, adolescents overwhelmingly report anxiety, depression, and stress have become their biggest barriers to learning.

Gotlib and his team plan to scan the teenagers again as they turn 20, to determine whether their brains return to their pre-pandemic developmental trajectory or if the changes continue over time. 鈥淲e don鈥檛 know if this is going to persist or if this is simply a temporary response to the stress of a pandemic,鈥 he said. 鈥淭he accelerated aging could slow to put them back on track to their chronological age.鈥

They have already been able to predict which teenagers would be based on their previous neurological development; for example, those who had more stable brain development previously were less likely to internalize toxic stress through depression.

The researchers are also starting to work with another team in Singapore, which has been tracking developmental changes to younger children during the pandemic.

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A version of this article appeared in the January 18, 2023 edition of Education Week as Teen Brains Aged Prematurely During the Pandemic. 69传媒 Should Take Note

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